During a blizzard in 1964, Dr. David Henry delivers his son Paul with the help of nurse Caroline. But when Henry realizes his wife is also carrying a girl with Down syndrome, he hands the second child over to Caroline without his wife's knowledge. Henry's fateful decision yields grave consequences for his family over the next 20 years.

Calvin Campbell is a former professional baseball player sent to an early retirement due to his panic attacks at the plate. Even though he had all the talent for the big leagues, he struggles with the curveballs life has thrown him. Today, he mindlessly sleepwalks through his days and the challenge of raising his teenager daughter. His life is in a slow downward spiral when it is suddenly awakened and invigorated by the most unlikely person – Produce, a young-man with Down syndrome who works at the local grocery store.

Up-and-coming sports reporter rescues a homeless man ("Champ") only to discover that he is, in fact, a boxing legend believed to have passed away. What begins as an opportunity to resurrect Champ's story and escape the shadow of his father's success becomes a personal journey as the ambitious reporter reexamines his own life and his relationship with his family.

Middle-aged widow Beatrice Hunsdorfer and her daughters Ruth and Matilda are struggling to survive in a society they barely understand. Beatrice dreams of opening an elegant tea room but does not have the wherewithal to achieve her lofty goal. Epileptic Ruth is a rebellious adolescent, while shy but highly intelligent and idealistic Matilda seeks solace in her pets and school projects, including one designed to show how small amounts of radium affect marigolds.

Devoted teacher Anne Sullivan leads deaf, blind and mute Helen Keller out of solitude and helps integrate her into the world.

A chronicle of three weeks in the lives of several high school teachers, administrators and students through the eyes of substitute teacher, Henry Barthes. Henry roams from school to school, imparting modes of knowledge, but never staying long enough to form any semblance of sentient attachment.

Maggie has had four children, by four different fathers, removed by social services because of a previous violent relationship. When she meets Jorge, a gentle Latin American refugee, she gradually sees her chance for happiness, but her past still haunts her.

The fantastical tale of a little girl who won't - or can't - follow the rules. Confounded by her clashes with the rule-obsessed world around her, Phoebe seeks enlightenment from her unconventional drama teacher, even as her brilliant but anguished mother looks to Phoebe herself for inspiration.

An optimistic, talented teen clings to a huge secret: she's homeless and living on a school bus. When tragedy strikes, can she learn to accept a helping hand?

Jo, the mother of seven children, divorces her second husband in order to marry Jake, a successful but promiscuous screenwriter. Though they are physically and emotionally compatible, they are slowly torn apart.

When Billy returns from reform school he has to attend a different high school at the other side of town. He tries to start with a clean slate but his old rival doesn't make it easy on him and his buddy Louie tries to make him go astray again. His brother Joe, quite the opposite of Billy, is a good runner and determined to win a track scholarship. He suggests Billy to join his school's track team, which pits the two brothers against each other.

A busy executive learns during a meeting that his mother may be dying and rushes home to her side. He ends up being his father's caretaker and becomes closer to him than ever before. Estranged from his own son, the executive comes to realize what has been missing in his own life.

A man living in the towering shadow of his aging father finds it difficult to start a new chapter in his life by marrying his girlfriend and moving to California.

The true story of the frightening, lonely world of silence and darkness of 7-year-old Helen Keller who, since infancy, has never seen the sky, heard her mother's voice or expressed her innermost feelings. Then Annie Sullivan, a 20-year-old teacher from Boston, arrives. Having just recently regained her own sight, the no-nonsense Annie reaches out to Helen through the power of touch, the only tool they have in common, and leads her bold pupil on a miraculous journey from fear and isolation to happiness and light.

94-year-old Eleanor Morgenstein tries to rebuild her life after the death of her best friend. As a result, she moves back to New York City after living in Florida for decades.

School nurse Alice Goodwin lives with her husband and two daughters on a dairy farm in a small Wisconsin community. After an accident on her property involving a friend's child, the town turns against her and Alice finds herself fighting charges of child abuse.

A psychotherapist helps a law student cope with schizophrenia in one of five interconnected tales dealing with mental illness.

When lapsed Jew and former cardiologist Harry suddenly decides to spend his retirement as a pig farmer in Nazareth, Israel, the move deeply shocks his family and his new neighbours. Back in New York, Harry’s ex-wife Monica is trying to manage the lives of their adult children, Annabelle and David, as well as her own.

Carla Zachanassian had a child by Serge Miller as a teenager. When Serge refused to marry her, she was driven out of town. By her own wit and cunning, she has returned as a multi-millionaire for a visit. The town lays out the red carpet expecting big things from Carla, only to learn that her sole purpose is to see Serge Miller killed...

Freshman high-school student Melinda has refused to speak ever since she called the cops on a popular summer party. With her old friends snubbing her for being a rat, and her parents too busy to notice her troubles, she folds into herself, trying to hide her secret: that star senior Andy raped her at the party. But Melinda does manage to find solace in her art class headed by Mr. Freeman.