In early 20th-century Montana, Col. William Ludlow lives on a ranch in the wilderness with his sons, Alfred, Tristan, and Samuel. Eventually, the unconventional but close-knit family are bound by loyalty, tested by war, and torn apart by love, as told over the course of several decades in this epic saga.

A man and his partner arrive at a small Western town to kill its most powerful man because the former blames him for his wife's death.

Jim Douglass arrives in the small town of Rio Arriba in order to witness the hanging of the four men he believes murdered his wife. When the convicts escape, Jim tracks them into Mexico, determined to see that justice is done. But the farther Jim goes in his quest for vengeance, the more merciless he becomes, losing himself in an unrelenting spiral of hatred and violence.

A group of unlikely travelling companions find themselves on the same stagecoach to Cheyenne. They include a drunken doctor, a bar girl who's been thrown out of town, a professional gambler, a travelling liquor salesman, a banker who has decided to embezzle money, a gun-slinger out for revenge and a young woman going to join her army captain husband. All have secrets but when they are set upon by an Indian war party and then a family of outlaws, they find they must all work together if they are to stay alive.

A powerful rancher always protects his wild adult son by paying for damages and bribing witnesses, until his crimes become too serious to rectify.

Cowboy John O'Hanlan is surprised to learn that someone's left him a business in Cheyenne, Wyoming. He sets out to claim it, only to discover it's a brothel.

Karl Westover, an inexperienced farm boy, runs away after unintentionally killing a neighbor, whose family pursues him for vengeance. He meets Barbarosa, a gunman of near-mythical proportions, who is himself in danger from his father-in-law Don Braulio, a wealthy Mexican rancher. Don Braulio wants Barbarosa dead for marrying his daughter against the father's will. Barbarosa reluctantly takes the clumsy Karl on as a partner, as both of them look to survive the forces lining up against them.

Blaise Starrett is a rancher at odds with homesteaders when outlaws hold up the small town. The outlaws are held in check only by their notorious leader, but he is diagnosed with a fatal wound and the town is a powder keg waiting to blow.

Texas Ranger Jake Cutter arrests gambler Paul Regret, but soon finds himself teamed with his prisoner in an undercover effort to defeat a band of renegade arms merchants and thieves known as Comancheros.

Beautiful half-breed Pearl Chavez becomes the ward of her dead father's first love and finds herself torn between her sons, one good and the other bad.

John Breen (John Wayne), a Kentucky militiaman falls in love with French exile Fleurette De Marchand (Vera Ralston). He discovers a plot to steal the land that Fleurette's exiles plan to settle on and aims to foil it.

Despite trying to keep his swashbuckling to a minimum, a threat to California's pending statehood causes the adventure-loving Don Alejandro de la Vega and his wife, Elena, to take action.

Pacer Burton, a young man of mixed Kiowa and white heritage, is caught between two worlds as conflict erupts between Native Americans and white settlers in Texas.

An authoritarian rancher rules an Arizona county with her private posse of hired guns. When a new Marshal arrives to set things straight, the cattle queen finds herself falling for the avowedly non-violent lawman. Both have itchy-fingered brothers, a female gunman enters the picture, and things go desperately wrong.

Two black bounty hunters ride into a small town out West in pursuit of an outlaw. They discover that the town has no sheriff, and soon take over that position, much against the will of the mostly white townsfolk.

Wild Bill Hickok, Calamity Jane, and Buffalo Bill go up against Indians and a gunrunner.

A female hustler is chasing after rich men, but becomes repeatedly mixed up with a suave con man and card shark through a series of misadventures before falling in love with him.

A buffalo hunter has a falling-out with his partner, who kills for fun.

A con artist arrives in a mining town controlled by two competing companies. Both companies think he's a famous gunfighter and try to hire him to drive the other out of town.

Davy Crockett and his sidekick Georgie compete against boastful Mike Fink ("King of the River") in a boat race to New Orleans. Later, Davy and Georgie, allied with Fink, battle a group of river pirates trying to pass themselves off as Native Americans.