Devoted teacher Anne Sullivan leads deaf, blind and mute Helen Keller out of solitude and helps integrate her into the world.

Rose and her daughter Sofia travel to the Spanish seaside town of Almería to consult with the shamanic Dr. Gomez, a physician who could possibly hold the cure to Rose’s mystery illness, which has left her bound to a wheelchair. But in the sultry atmosphere of this sun-bleached town Sofia, who has been trapped by her mother’s illness all her life, finally starts to shed her inhibitions, enticed by the persuasive charms of enigmatic traveller Ingrid.

Middle-aged widow Beatrice Hunsdorfer and her daughters Ruth and Matilda are struggling to survive in a society they barely understand. Beatrice dreams of opening an elegant tea room but does not have the wherewithal to achieve her lofty goal. Epileptic Ruth is a rebellious adolescent, while shy but highly intelligent and idealistic Matilda seeks solace in her pets and school projects, including one designed to show how small amounts of radium affect marigolds.

Calvin Campbell is a former professional baseball player sent to an early retirement due to his panic attacks at the plate. Even though he had all the talent for the big leagues, he struggles with the curveballs life has thrown him. Today, he mindlessly sleepwalks through his days and the challenge of raising his teenager daughter. His life is in a slow downward spiral when it is suddenly awakened and invigorated by the most unlikely person – Produce, a young-man with Down syndrome who works at the local grocery store.

Precocious young Harriet and her older sister Gwen live at their mother's motel in small-town New Hampshire. Harriet dreams of a life beyond her inattentive family and the stultifying town. A mentally disabled man named Ricky comes to stay at the motel, and Harriet finds him kinder and more interesting than anyone she has ever met. After tragedy strikes, Harriet and Ricky cling to each other ever more tightly.

Anthony Richmond schemes to get the fortune of his tyrannical, wheelchair-using tycoon uncle Charles Richmond by persuading Maria, a nurse he employs, to marry him.

A 10-year-old boy spends a summer in the country with a childless couple and a precocious girl.

Paul, a 20 year old midwesterner, arrives at the central bus station and quickly catches eyes with Wye, a 22 year old girl voguing on the sidewalk. After Paul seeks her out in secret, an intense love between them blossoms. But when Paul discovers Wye is trans, he is forced to confront his own identity and what it means to belong.

A significantly deformed but highly intelligent teenage boy and his biker gang mother attempt to live as normal a life as possible under the circumstances.

In this David vs. Goliath drama based on a true story, college professor Robert Kearns goes up against the giants of the auto industry when they fail to give him credit for inventing intermittent windshield wipers. Kearns doggedly pursues recognition for his invention, as well as the much-deserved financial rewards for the sake of his wife and six kids.

When fifteen-year-old Tyson attends public school for the first time, his life is changed forever. While helping his father clean up after the football team, Tyson befriends champion marathon runner Aklilu. Never letting his autism hold him back, Tyson becomes determined to run his first marathon in hopes of winning his father's approval. With the help of an unlikely friend and his parents, Tyson learns that with faith in yourself and the courage to take the first step, anything is possible.

94-year-old Eleanor Morgenstein tries to rebuild her life after the death of her best friend. As a result, she moves back to New York City after living in Florida for decades.

A psychotherapist helps a law student cope with schizophrenia in one of five interconnected tales dealing with mental illness.

A woman embarks on a journey alone across the United States after fleeing from her violent husband.

Jo, the mother of seven children, divorces her second husband in order to marry Jake, a successful but promiscuous screenwriter. Though they are physically and emotionally compatible, they are slowly torn apart.

During a blizzard in 1964, Dr. David Henry delivers his son Paul with the help of nurse Caroline. But when Henry realizes his wife is also carrying a girl with Down syndrome, he hands the second child over to Caroline without his wife's knowledge. Henry's fateful decision yields grave consequences for his family over the next 20 years.

Corinne is a single mother of twin 5-year-old boys, Steven and Phillip, who are diagnosed with autism. Public school officials threaten to remove them from school due to their behavior, but through therapy, the boys are able to make major strides in their capabilities. A decade later, teens Steven and Phillip seek to prove they can handle high school while still struggling with their disorder.

After cancer claims Matt Kell's life on Christmas Day 2005, his widow, Gina and two young boys are left to cope with the pain of his loss while their close church community gathers around them for support.

Tells the incredible true story of Amberley Snyder, a nationally ranked rodeo barrel racer who defies the odds after barely surviving a car accident that leaves her paralyzed from the waist down.

A young man with a bright future suffers a near-fatal accident and recreates his new life with the help of an unlikely animal friend.