After breaking up with her girlfriend, a nightclub singer, Jane, answers a personal ad from Robin, a real estate agent with AIDS, seeking a cross-country travel partner. On their journey from New York City to Los Angeles, the two stop by Pittsburgh to pick up Jane's friend Holly, who is trying to escape an abusive relationship. With three distinct personalities, the women must overcome their differences to help one another.

Two drifters bum around, visit earthy women and discuss opening a car wash in Pittsburgh.

A young man with Tourette's Syndrome embarks on a road trip with his recently-deceased mother's ashes.

A terminally ill man and his teenage daughter embark on a road trip from California to New Orleans for his 20th college reunion. While there, he secretly hopes she can reunite with the mother who left them long ago.

While caring for her brother along with her audacious mother, a teenager strikes up an unlikely friendship with an eccentric activist who is protesting one of the most landmark medical cases of all time.

Self-described misanthrope Elle Reid has her protective bubble burst when her 18-year-old granddaughter, Sage, shows up needing help. The two of them go on a day-long journey that causes Elle to come to terms with her past and Sage to confront her future.

Newly widowed Frank Fogle embarks on a journey to Ireland to scatter his late wife’s ashes. His estranged son, Sean, recently released from prison, agrees to join only when his father promises that they’ll never see each other again following the trip. After revelations surface about an old flame of Frank’s wife and a charming hitchhiker with plans of her own intervenes, father and son find themselves drawn together in unexpected ways.

Two high school girls are best friends until one dates the other's older brother, who is totally his sister's nemesis.

Nina Geld's passion and talent have made her a rising star in the comedy scene, but she's an emotional mess offstage. When a new professional opportunity coincides with a romantic one, she is forced to confront her own deeply troubled past.

An emotionally desperate investment banker finds hope through a woman he meets.

A man in his mid-20s, still living at home with his mother and stepfather, puts all his eggs in one basket: the girl who works at his local coffee shop. The problem is, she has a serious boyfriend. As they become closer, the line between friendship and intimacy is blurred, and the situation forces both to examine where they are in their lives.

On an empty road in the middle of the night, Shula stumbles across the body of her uncle. As funeral proceedings begin around them, she and her cousins bring to light the buried secrets of their middle-class Zambian family.

An eclectic band of misfits becomes an unlikely family as they take a wild journey in the name of love while on the run from an overzealous FBI duo who want them dead or alive - preferably dead.

In the aftermath of his girlfriend's mysterious death, a young man awakens to strange horns sprouting from his temples.

After discovering she can’t legally get an abortion in Missouri without her parents’ permission, teenager Veronica convinces her former best friend Bailey to take a road trip to Albuquerque to seek the procedure.

When his husband unexpectedly dies, Marc's world shatters, sending him and his two best friends on a soul-searching trip to Paris that reveals some hard truths they each needed to face.

When Audrey's business trip to Asia goes sideways, she enlists the aid of Lolo, her irreverent, childhood best friend who also happens to be a hot mess; Kat, her college friend turned Chinese soap star; and Deadeye, Lolo's eccentric cousin. Their no-holds-barred, epic experience becomes a journey of bonding, friendship, belonging, and wild debauchery that reveals the universal truth of what it means to know and love who you are.

Four young women continue the journey toward adulthood that began with "The Sisterhood of the Traveling Pants." Now three years later, these lifelong friends embark on separate paths for their first year of college and the summer beyond, but remain in touch by sharing their experiences with each other.

Eric returns home for a short visit and finds himself caught between reuniting with his sisters and chasing a victory with his old poker group. As the trip extends, Eric finds it increasingly difficult to avoid confrontations and revelations as his carefully constructed façade of his adulthood gives way to old childhood conflicts.

Nerdy accountant Harold and his irrepressible friend, Kumar, get stoned watching television and find themselves utterly bewitched by a commercial for White Castle. Convinced there must be one nearby, the two set out on a late-night odyssey that takes them deep into New Jersey. Somehow, the boys manage to run afoul of rednecks, cops and even a car-stealing Neil Patrick Harris before getting anywhere near their beloved sliders.