Following the death of his wife, a young father's hold on reality crumbles, and a strange presence begins to stalk him from the shadowy recesses of the apartment he shares with his two young sons.

On the outside, Helen has it all – a loving family and a successful career – but when her suppressed mental illness resurfaces, the world crumbles around her. Crippled by depression, Helen finds solace through her friendship with Mathilda, a kindred spirit struggling with bipolar disorder.

After her stay-at-home husband leaves her, a workaholic lawyer finds that she is not completely up to the tasks of caring for her young son, ailing father and household all by herself.

Years after her son's suicide, a woman longs to confront both the past and a friend of his who took his business idea.

David Sinclair seems to have everything going for him: he's smart, musically talented, and very successful. To top off his senior year in high school, his band is trying to get a recording session. Therefore, David's suicide leaves everyone, especially his best friend and bandmate, Chris, with a lot of questions.

In a suburban landscape, the lives of several families interlace with loss, despair and personal crisis. Esther Gold has lost focus on all but caring for her comatose son, Paul, and neglects her daughter and husband. Lawyer Jim Train is devoted to his career, not his family. Helen Christianson wants to find a new spark in life, while Annette Jennings tries to rebuild hers.

Grief-stricken after the loss of her child, Vanessa takes refuge at a lake house only to be met with an aberration of herself from a parallel universe and realizes the multiverse gates hold the key to releasing her grief or trapping her forever.

A detective becomes obsessed with solving a child's 50-year-old murder, uncovering striking similarities between the case and his son's disappearance.

Lila, a grief-stricken mother reeling from her son’s murder, attends a support group where she meets Eve, who urges her to take matters into her own hands to track down her son’s killers.

The drug-induced utopias of four Coney Island residents are shattered when their addictions run deep.

Portland, Oregon, 1971. Bob Hughes is the charismatic leader of a peculiar quartet, formed by his wife, Dianne, and another couple, Rick and Nadine, who skillfully steal from drugstores and hospital medicine cabinets in order to appease their insatiable need for drugs. But neither fun nor luck last forever.

After her boyfriend commits suicide, a young woman attempts to use the unpublished manuscript of a novel and a sum of money he left behind to reinvent her life.

Suffering from a severe case of depression, toy company CEO Walter Black begins using a beaver hand puppet to help him open up to his family. With his father seemingly going insane, adolescent son Porter pushes for his parents to get a divorce.

A young girl whose father is an ex-convict and whose mother is a junkie finds it difficult to conform and tries to find comfort in a quirky combination of Elvis and the punk scene.

An awkward office drone becomes increasingly unhinged after a charismatic and confident look-alike takes a job at his workplace and seduces the woman he desires.

The recently widowed mother of two, Sarah, is desperate to know who murdered her husband in front of her young son, rendering him mute. Coerced into helping a low-life drug dealer stash narcotics stolen from the local Mr. Big, she's forced into taking drastic action to protect her children, evolving from downtrodden submissive to take-charge vigilante.

A psychic's ominous reading sends a man into a tailspin.

Controversy and legal problems follow Dr. Jack Kevorkian as he advocates assisted suicide.

A ticking-time-bomb insomniac and a slippery soap salesman channel primal male aggression into a shocking new form of therapy. Their concept catches on, with underground "fight clubs" forming in every town, until an eccentric gets in the way and ignites an out-of-control spiral toward oblivion.

A New York couple's relationship is tested after the loss of their child. This film is the wide-released combination of the original two :him and :her volumes that premiered at the Cannes Film Festival.