Vincent Bruce, a war veteran, begins working as an occupational therapist at Poplar Lodge, a private psychiatric facility for wealthy people where he meets Lilith Arthur, a charming young woman suffering from schizophrenia, whose fragile beauty captivates all who meet her.

A woman becomes very curious about one of her psychiatrist husband's inmates, a man who was found guilty in the murder and disfigurement of his former wife.

Virginia Cunningham is confused upon finding herself in a mental hospital, with no memory of her arrival at the institution. Tormented by delusions and unable to even recognize her husband, Robert, she is treated by Dr. Mark Kik, who is determined to get to the root of her mental illness. As her treatment progresses, flashbacks depict events in Virginia's life that may have contributed to her instability.

A woman turns to prescription medication as a way of handling her anxiety concerning her husband's upcoming release from prison.

A troubled Southern man talks to his suicidal sister's psychiatrist about their family history and falls in love with her (and New York City) in the process.

In New York City, the lives of a lawyer, an actuary, a house-cleaner, a professor, and the people around them intersect as they ponder order and happiness in the face of life's cold unpredictability.

With her life crashing down around her, Linda attempts to navigate her child's mysterious illness, her absent husband, a missing person, and an increasingly hostile relationship with her therapist.

Zach Riley is a psychiatrist, who leaves a job at a prestigious university, to take up a job at the privately run mental institution, Millwood. What he doesn't reveal at the time of his appointment is that this was the very place where his novelist father, T.L. Pierson, spent many years of his life.

A petty criminal fakes insanity to serve his sentence in a mental ward rather than prison. He soon finds himself as a leader to the other patients—and an enemy to the cruel, domineering nurse who runs the ward.

World War II soldier-turned-U.S. Marshal Teddy Daniels investigates the disappearance of a patient from a hospital for the criminally insane, but his efforts are compromised by troubling visions and a mysterious doctor.

After leaving his wife, lawyer Jerry Ryan moves from Omaha, Nebraska to New York City to start a new life. While studying for the New York Bar Examination and working to finalize his divorce, Ryan meets dancer Gittel Mosca, and the two begin a cautious courtship. However, Ryan feels that he must come to terms with his failed marriage and overcome his lingering attachment to his ex-wife before he can redefine himself and embrace his budding romance.

After losing her sight while working as a photojournalist in Afghanistan, Sara Frost, now reclusive, lives quietly in a New York penthouse with her boyfriend, until a smooth but sadistic criminal looking for a hidden fortune enters her life.

A suicidal young man is committed to a Dublin psychiatric hospital where he meets new friends who greatly influence his life.

A young heroin addict roams the streets of New York to panhandle and get her next fix, while her unstable boyfriend drifts in and out of her life at random.

A bureaucrat interviews five souls to decide which of them will be given a life on Earth. But he soon faces an existential challenge of his own.

A single mother and an incarcerated man forge an unlikely bond through heartfelt letters, unlocking a door to redemption, hope and love against all odds.

Matthew, a young schizophrenic, finds himself out on the street when a slumlord tears down his apartment building. Soon, he finds himself in even more dire straits, when he is threatened by Little Leroy, a thug who is one of the tough denizens of the Fort Washington Shelter for Men. He reaches out to Jerry, a streetwise combat veteran, who takes Matthew under his wing as a son. The relationship between these two men grows as they attempt to conquer the numbing isolation of homelessness.

Set in the changing world of the late 1960s, Susanna Kaysen's prescribed "short rest" from a psychiatrist she had met only once becomes a strange, unknown journey into Alice's Wonderland, where she struggles with the thin line between normal and crazy. Susanna soon realizes how hard it is to get out once she has been committed, and she ultimately has to choose between the world of people who belong inside or the difficult world of reality outside.

London is a drug laden adventure that centers on a party in a New York loft where a young man is trying to win back his ex-girlfriend.

On the outside, Helen has it all – a loving family and a successful career – but when her suppressed mental illness resurfaces, the world crumbles around her. Crippled by depression, Helen finds solace through her friendship with Mathilda, a kindred spirit struggling with bipolar disorder.